SBIR / Technical Proposal Coherence Review

AURA — Phase I Neuromodulation Feasibility Proposal

Medical device · NIH-style feasibility review · Representative excerpt

What this excerpt demonstrates

Technical proposal risk diagnosis
Biological delivery-chain audit
Claim matrix — assertions mapped to mechanisms
Phase I aim structure and go/no-go ladder
Milestone and reviewer-framing repair

Excerpt document

Review summary

AURA is a Phase I SBIR proposal for a non-invasive neuromodulation platform targeting cranial nerve engagement via external transducer geometry. The review identifies the core unresolved engineering chain:

Pad geometry → tissue field distribution → cranial-nerve engagement → physiological signal → development path

Each link in this chain is a separate feasibility question. The proposal as submitted treats the chain as a single claim. The review separates each link into a testable Phase I aim, assigns evidence requirements, and identifies missing measurements that must be present for a responsive reviewer to score the technical section.

The claim matrix, reviewer objection map, and Phase I aim structure are included in the excerpt PDF.

Full review document available upon request. Contact [email protected] with subject: AURA full review request.

REPRESENTATIVE PORTFOLIO EXCERPT This document is based on an InTelluric-originated technical concept and contains no client confidential information. It demonstrates pre-submission technical review format and does not represent a submitted grant application, regulatory opinion, investment advice, legal advice, government endorsement, or clinical claim.